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. Author manuscript; available in PMC: 2016 Aug 28.
Published in final edited form as: Eur J Med Chem. 2015 Jun 16;101:384–390. doi: 10.1016/j.ejmech.2015.06.031

Table 5.

Evaluation of metabolic stability of compound 13, verapamil, and warfarin in human liver microsomes.

Compound/Drug
Tested		 Average
remaining after
60 min (%), with
NADPH		 Average
remaining after
60 min (%),
without NADPH		 Notes
13 24 51 -
Verapamil 13 94 High metabolism control
Warfarin 93 94 Low metabolism control