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. 2015 Dec 22;5:17559. doi: 10.1038/srep17559

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(a) PCSK9 concentrations in the serum of women with healthy fetuses at different GAs. (b) PCSK9 levels in the sera of women with fetuses with NTDs and healthy fetuses at different GAs (GA 15–20 w, 23–27 w, 37–40 w). (c) ROC analysis for PCSK9 to discriminate NTDs from controls. **p < 0.01.