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. 2015 Dec 21;11(12):e1004659. doi: 10.1371/journal.pcbi.1004659

Fig 7. Conservation of local frustration at the contact-level.

Fig 7

A) Contact map for a consecutive pair of ANK repeats. In the upper matrix the most informative state from the frustration IC calculations is shown. Red represents that the most informative state is the highly frustrated, gray is for the neutral state and green when the minimally frustrated state is the most informative one. Those values are calculated over the absolute counts that occur for each canonical interaction in the dataset. In the lower matrix the relative frequency of having a contact between two canonical positions in the repeats pair is shown in grey-scale where darker points mean that the interaction is present in a bigger fraction of the repeats being analyzed. B) Conservation of interactions in and between repeats: Contacts within the ankyrin repeat with a IC value higher than the highest interaction where the neutral state is the most informative. Residues involved in these conserved interactions are marked: Most conserved amino acid(s): Yellow: Position 8; G. Blue: Positions 11–14;TPLH. Orange: Positions 15–16; AA. Red: Positions 23–24; IV. C) Conservation of most informative contacts at the interface between repeats.