Table 1. Three kinase fusion transcripts in endometrial cancer.
| Cell line | 5′-Gene | 3′-Gene | Locus 5′-Gene | Locus 3′-Gene | 5′-Gene copy number* | 3′-Gene copy number* | Discordant read (n) | Junction spanning read (n) | Frequency in clinical specimens |
|---|---|---|---|---|---|---|---|---|---|
| JHUEM3 | CPQ | PRKDC | 8q22.1 | 8q11.21 | 2 | 2 | 16 | 44 | 3/122 (2.5%) |
| HEC59 | CAPZA2 | MET | 7q31.2 | 7q31.2 | 0 | 1 | 8 | 27 | 0/122 (0%) |
| AN3CA | VGLL4 | PRKG1 | 3p25.3 | 10q21.1 | −2 | 1 | 19 | 21 | 0/122 (0%) |
*Putative copy number was determined by GISTIC2 (−2 = homozygous deletion; −1 = hemizygous deletion; 1 = low level gain; 2 = high level amplification)