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. 2015 Dec 21;10(12):e0145404. doi: 10.1371/journal.pone.0145404

Fig 6. Chemotherapeutic drugs cause increased release of pro-inflammatory molecules from MM cells.

Fig 6

(A) Hmeso MM cells treated with either Dox or cisplatin caused increased release of HMGB1, FGF2, IL-1β and IL-18 as measured by Western blot analysis or ELISA. No loading controls were included as analysis was performed in cell culture medium. (B) H2373 MM cells also showed increased release of various pro-inflammatory molecules in response to drugs. IL-6 levels were either decreased (H2373) or not significantly changed (Hmeso) by drug treatments. *p≤0.05 as compared to untreated controls (0).