. 2015 Dec 21;10(12):e0145404. doi: 10.1371/journal.pone.0145404

Table 1. NLRP3 regulation by Doxorubicin + inhibitors in Hmeso MM cells ^† .

Inhibitor	NLRP3	Caspase-1	HMGB1
CA-074Me (Cathepsin B)	↓^*	↑^***	↑^**
Cytochalasin D (Actin Polymerization)	↑^***	↑^*	↑^*
KCl (K+ Efflux)	↓	↑^**	No change
KN-62 (ATP)	↓^*	↑	No change
NAC (ROS)	↑	↓^**	No change

†Upward arrow: increased; downward arrow: decreased; arrows with stars: significant changes; arrows without stars: changes did not reach significance; No change: no difference between groups.

*p≤0.05

**p≤0.01

***p≤0.001

Table 1. NLRP3 regulation by Doxorubicin + inhibitors in Hmeso MM cells † .

Table 1. NLRP3 regulation by Doxorubicin + inhibitors in Hmeso MM cells ^† .