. 2015 Dec 21;10(12):e0145404. doi: 10.1371/journal.pone.0145404

Table 2. NLRP3 regulation by Cisplatin + inhibitors in Hmeso MM cells ^† .

Inhibitor	NLRP3	Caspase-1	HMGB1
CA-074Me (Cathepsin B)	↑^*	No change	No change
KN-62 (ATP)	↑^*	↑^*	↑^**
NAC (ROS)	↓	↑^, ↓^*	↓

†Upward arrow: increased; downward arrow: decreased; arrows with stars: significant changes; arrows without stars: changes did not reach significance; No change: no difference between groups.

*p≤0.05

**p≤0.01

Table 2. NLRP3 regulation by Cisplatin + inhibitors in Hmeso MM cells † .

Table 2. NLRP3 regulation by Cisplatin + inhibitors in Hmeso MM cells ^† .