Table 1.
Baseline patient data and univariate analysis of factors associated with survival at 60 months
| Type | Group | Subgroup | Survivor (N = 77) | Deceased (N = 30) | P value |
|---|---|---|---|---|---|
| Demographic data | Age (years) | 59.65 ± 12.75 | 58.27 ± 12.58 | 0.614 | |
| Gender | Male | 50 (64.9 %) | 21 (70 %) | 0.618* | |
| Female | 27 (35.1 %) | 9 (30 %) | |||
| Pathologic factors | Colorectum | Colon cancer | 45 (58.4 %) | 15 (50 %) | 0.389* |
| Rectal cancer | 31 (40.3 %) | 15 (50 %) | |||
| Tumor size (cm) | 5.0 (2.0, 10.0) | 3.7 (1.0, 10.0) | 0.017 | ||
| TNM stage | Tis | 2 (2.6 %) | 0 | <0.001* | |
| I | 15 (19.5 %) | 0 | |||
| IIA | 21 (27.3 %) | 1 (3.3 %) | |||
| IIB | 10 (13.0 %) | 2 (6.7 %) | |||
| III | 24 (31.2 %) | 14 (46.7 %) | |||
| IV | 5 (6.5 %) | 13 (43.3 %) | |||
| Histologic type | Adenocarcinoma | 67 (87.0 %) | 26 (86.7 %) | 0.436* | |
| Mucinous adenocarcinoma | 3 (3.9 %) | 3 (10.0 %) | |||
| Signet ring cell carcinoma | 1 (1.3 %) | 0 | |||
| Adenocarcinoma with component of mucinous adenocarcinoma | 3 (3.9 %) | 1 (3.3 %) | |||
| Adenocarcinoma with component of signet ring cell carcinoma | 1 (1.3 %) | 0 | |||
| Other | 2 (2.6 %) | 0 | |||
| Differentiation degree | Well differentiated | 4 (5.2 %) | 0 | 0.054* | |
| Well or moderately differentiated | 4 (5.2 %) | 0 | |||
| Moderately differentiated | 54 (70.1 %) | 24 (80.0 %) | |||
| Moderately or poorly differentiated | 8 (10.4 %) | 3 (10.0 %) | |||
| Poorly differentiated | 5 (6.5 %) | 1 (3.3 %) | |||
| Undifferentiated | 1 (1.3 %) | 1 (3.3 %) | |||
| Nodal metastasis | 0 (0,12) | 2 (0,9) | 0.01 | ||
| Ratio of nodal metastasis to retrieved nodes | 0 % (0 %, 100 %) | 8.93 % (0, 100) | 0.03 | ||
| Immunohistochemical factors | PCNA | 60 % (0 %, 95 %) | 52.5 % (10, 85) | 0.129 | |
| nm23 | 0 = "(–)" | 9 (11.7 %) | 5 (16.7 %) | 0.65* | |
| 1 = "(±)" | 11 (14.3 %) | 2 (6.7 %) | |||
| 2 = "(+)" | 51 (66.2 %) | 22 (73.3 %) | |||
| 3 = "(++)" | 2 (2.6 %) | 0 | |||
| 4 = "(+++)" | 4 (5.2 %) | 1 (3.3 %) | |||
| Cyclin D1 | 0 = "(–)" | 14 (18.2 %) | 3 (10.0 %) | 0.03* | |
| 1 = "(±)" | 28 (36.4 %) | 5 (16.7 %) | |||
| 2 = "(+)" | 31 (40.3 %0 | 15 (50.0 %) | |||
| 3 = "(++)" | 3 (3.9 %) | 6 (20.0 %) | |||
| 4 = "(+++)" | 1 (1.3 %) | 1 (3.3 %) | |||
| Ki67 | 50 (0,95) | 45 (5,90) | 0.908 | ||
| Maximum standardized uptake value | SUVmax | 9.8 (4.4, 24.7) | 13.6 (3.2, 34.2) | <0.001 |
There is one missing number in “Colon or Rectal cancer” in the survivor group. And each group had a missing in “Differentiation degree”
*Means data was shown in number (percentage) and analyzed by Chi-square test. And the other data are all shown in median (minimum, maximum) and analyzed by ANOVA