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. 2015 Dec 21;34:153. doi: 10.1186/s13046-015-0271-1

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© Wei et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Characteristics of rNDV-18HL. a Proliferation dynamic of rNDV-18HL. BHK-21 cells were infected with either rNDV-18HL or NDV Italien at MOI = 0.01. At 6, 12, 24, 36, 48, and 72 h post-infection, culture supernatants were collected and the viral titer was determined (TCID₅₀/ml) (n = 3). b Cytotoxicity assay of rNDV-18HL. SMMC-7721, HuH-7, and HuH-7 cells were infected with either rNDV-18HL or NDV Italien for 7 days. The cell viability was measured using MTT assay (n = 5). The cell viability of the three HCC cell lines at 7 days post-infection was shown in (c)