Table 1.
Haematology and blood biochemistry measurements (mean ± SEM) of spontaneously hypertensive rats (SHR)
| Parameters | PBS | NC8 | RLP |
|---|---|---|---|
| WBC (109/L) | 5.133 ± 1.935 | 5.567 ± 0.929 | 5.400 ± 2.272 |
| RBC (1012/L) | 6.810 ± 0.764 | 6.727 ± 0.748 | 7.620 ± 0.735 |
| HGB (g/L) | 94.33 ± 14.154 | 102.33 ± 6.658 | 113.00 ± 10.583 |
| HCT (%) | 0.308 ± 0.013 | 0.320 ± 0.047 | 0.382 ± 0.034* |
| MCV (fL) | 50.500 ± 0.700 | 50.000 ± 1.200 | 50.133 ± 0.351 |
| MCH (pg) | 14.133 ± 0.902 | 15.667 ± 0.757 | 14.833 ± 0.058 |
| MCHC (g/L) | 296.00 ± 30.610 | 314.00 ± 22.113 | 295.67 ± 1.155 |
| PLT (109/L) | 533.33 ± 59.181 | 589.33 ± 36.611 | 661.67 ± 289.096 |
| W-SCR (%) | 0.752 ± 0.064 | 0.607 ± 0.132 | 0.793 ± 0.159 |
| W-SCC (%) | 3.000 ± 0.600 | 3.133 ± 0.231 | 4.400 ± 2.193 |
| RDW-SD (fL) | 29.000 ± 0.100 | 29.033 ± 0.379 | 28.800 ± 0.625 |
| RDW-CV (%) | 0.147 ± 0.001 | 3.147 ± 5.198 | 0.148 ± 0.009 |
| PDW (fL) | 7.500 ± 0.100 | 7.733 ± 0.451 | 7.967 ± 0.643 |
| MPV (fL) | 6.200 ± 0.100 | 6.433 ± 0.231 | 6.700 ± 0.361 |
| P-LCR (%) | 0.030 ± 0.011 | 0.042 ± 0.009 | 0.047 ± 0.013 |
| UREA (mmol/L) | 8.343 ± 1.517 | 8.340 ± 0.963 | 7.700 ± 1.908 |
| GLUC (mmol/L) | 16.570 ± 2.370 | 14.300 ± 2.383 | 15.480 ± 1.019 |
| TCHE (mmol/L) | 1.360 ± 0.044 | 1.333 ± 0.125 | 1.100 ± 0.050*,# |
| TG (mmol/L) | 1.247 ± 0.025 | 1.213 ± 0.176 | 0.750 ± 0.181*,# |
The rats were divided into three groups and subjected to either PBS, L. planturm NC8 (NC8) or recombinant Lb.Plantarum NC8 (RLP) treatment for continuous 14 days, and then 5 rats from each group were selected at random at day 14 and the cardiac puncture samples were collected and the following values were measured
WBC white blood cell, RBC red blood cell, HGB haemoglobin, HCT hematocrit, MCV mean corpuscular volume, MCH mean corpuscular haemoglobin, MCHC mean corpuscular haemoglobin concentration, PLT platelet counts, W-SCR lymphocyte percentage, W-SCC absolute value of lymphocyte, PDW platelet distribution width, MPV mean platelet volume, P-LCR platelet large cell ratio, UREA urea nitrogen, GLUC total plasma glucose, TCHE total plasma cholesterol, TG triglyceride
The statistical significance was calculated using one way ANOVA.* P < 0.05 vs. PBS control. # P < 0.05 vs. NC8 control