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. 2015 Sep 15;45(10):1510–1522. doi: 10.1111/cea.12561

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© 2015 The Authors. Clinical & Experimental Allergy Published by John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Strong activin A immunolocalization in normal human airway epithelium is decreased in asthma. Lung tissue sections were stained immunohistochemically with antibody specific for the activin βA subunit (E4; IgG2b) (a, c, e, f) or rabbit anti-mouse IgG2b isotype control antibody (b, d). (a–d) Serial sections from normal human lung stained with βA-specific antibody or isotype control antibody. (e, f) Lung from a patient with severe asthma (e) and a patient with asthma and hypersensitivity pneumonitis (f). Immunoperoxidase, haematoxylin counterstain, original magnification 200×.