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. 2015 Oct 19;16(12):1688–1698. doi: 10.15252/embr.201540955

Figure EV1. Evolutionary conservation of sequence and structural features of XBP1‐BSL .

Figure EV1

  1. Multiple sequence alignment of XBP1‐BSL from phylogenetically diverse metazoans. Grey boxes: 7‐mer loops harboring the conserved cleavage sites. Dash‐outlined box: XBP1 intron.
  2. Secondary structures of select sequences in (A), and their corresponding spliced RNAs. Arrowheads: scissile bonds (unspliced structure); exon–exon junction (spliced structure). Closed circles: Watson–Crick base pairs. Open circles: Wobble base pairs. Colored arrows: stems in unspliced or spliced XBP1‐ BSL structures. S1, central stem; S2, S3, arm stems; ES1 extended stem.
  3. Secondary structures of select sequences in (A) showing the extension of S1.