Skip to main content
. 2015 Nov 2;37(1):47–55. doi: 10.3892/ijmm.2015.2399

Figure 5.

Figure 5

Effect of miR-375 on the Notch signaling pathway. (A) Luciferase reporter gene assay verification of the bioinformatics analysis-predicted NOTCH2 as a target gene of miR-375, **P<0.01. (B) NOTCH2, Delta-like 1 (DLL1) and hes family bHLH transcription factor 1 (HES1) mRNA expression levels detected by reverse transcription-quantitative polymerase chain reaction and normalized to GAPDH. Data are the mean ± standard deviation (SD) of three experiments, *P<0.05 and **P<0.01. (C) Western blotting demonstrating the inhibitory effect of miR-375 on the Notch signaling pathway. (D) Relative protein expression levels. Data are the mean ± SD of three experiments, *P<0.05 and **P<0.01.