(A) MIDA boronates uniformly show binary elution properties on silica gel thin-layer chromatography. (B) Photograph of the small molecule synthesizer which comprises three modules that execute the deprotection Ⓓ, coupling Ⓒ, and purification Ⓟ steps. (C) Automated synthesis of natural products, materials, pharmaceuticals, and biological probes via iterative coupling of building blocks indicated by different colors (24).