Table 1.
Association of certain follicular T helper cells (Tfh)‐like cell proportions with serological parameters.
Association | Disease | Variable | Correlation coefficient | P‐value |
---|---|---|---|---|
Positive | pSS | CD4+CXCR5+ICOS+PD‐1+ Tfh‐like cells versus levels of serum IgG antibody |
Spearman's R = 0·6143 |
0·0018 |
CD4+CXCR5+ICOS+PD‐1+ Tfh‐like cells versus levels of serum RF |
Spearman's R = 0·6219 |
0·0101 | ||
CD4+CXCR5+PD‐1+IL‐21+ Tfh cells versus levels of serum IC |
Pearson's R = 0·5734 |
0·0128 | ||
SLE | CD4+CXCR5+IL‐21+ Tfh cells versus levels of serum IC |
Spearman's R = 0·4723 |
0·0478 |
IC = immune complex; ICOS = inducible T cell co‐stimulator; Ig = immunoglobulin; PD‐1 = programmed death 1; pSS = primary Sjögren's syndrome; RF = rheumatoid factor; SLE = systemic lupus erythematosus.