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. 2015 Sep 11;183(1):37–49. doi: 10.1111/cei.12684

Figure 1.

Figure 1

Competitive binding by human antigen R (HuR) and Tis11 can direct alternative target mRNA fates. HuR and Tis11 can compete for the same binding sequences, resulting in opposing mRNA fates. (a) Competition for binding to target mRNA is determined by the affinity each RNA binding proteins (RBP) has to shared binding sequences. (b) The relative expression of these RBP will affect competitive binding. (c) Post‐translational regulation of RBP, for example via phosphorylation, affects their ability to bind to target mRNAs.