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. 2015 Nov 30;112(50):15474–15479. doi: 10.1073/pnas.1512915112

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Fig. 2. — Inhibited LTD but normal LTP in Numb-cKO mice. (A) Two consecutive PF EPSCs before (baseline) and after (t = 38 min) LTD induction in control (ctrl) and Numb-cKO PCs. The interval between paired EPSCs was 80 ms. (B) Time courses for percentage changes of EPSC1 amplitude in control (black) and Numb-cKO (gray) mice. Each data point was the average of three successive EPSCs evoked at 0.05 Hz. The arrow indicates LTD induction. (C) Time courses for PPF from the cells shown in B. (D) Example consecutive PF EPSCs before (baseline) and after (t = 38 min) LTP induction. (E) Time courses for percentage changes of EPSC1 amplitude in control (black) and Numb-cKO (gray) mice. (F) Time courses for PPF ratios from the subset of cells shown in E.