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. 2015 Dec 15;10(12):e0145018. doi: 10.1371/journal.pone.0145018

Fig 3. Differentiation of the soft palate muscles proceeds from the lateral regions to the midline.

Fig 3

(A-L) MHC (green) along the antero-posterior axis of the mouse soft palate at E13.5 (A-C), E14.5 (D-F), E15.5 (G-I), and P0 (J-L) at the level of the TVP and PLG (A, D, G, J), LVP (B, E, H, K), and PLP and SPC (C, F, I, L). (A) Dashed lines indicate the outline of the palatal shelf and tongue epithelium. Red arrows indicate the differentiated TVP. (D-E) In the inset, dashed lines correspond to the basal lamina of the palatal shelf epithelium, and the asterisk indicates the epithelial seam during the fusion process. Arrows indicate the medial region of the palatal shelf negative for mature myocytes until newborn stage. LVP: levator veli palatini, MP: medial pterygoid muscle, PLG: palatoglossus PLP: palatopharyngeus, SPC: superior pharyngeal constrictor, T: tongue, TT: tensor tympani, TG: trigeminal ganglion, TVP: tensor veli palatini. The schematic drawings indicate the orientation and the position of each section. Scale bars: 200μm.