TABLE I.
Characteristics of the study cohort
Characteristic | Value |
---|---|
Of the patients (n=24) | |
Age (years) | |
Median | 74.5 |
Range | 70–84 |
Sex [n (%) men] | 17 (70.8) |
Marital status [n (%)] | |
Married | 19 (86.4) |
Divorced or single | 3 (13.6) |
Unknown | 2 |
Have children [n (%)] | 21 (87.5) |
Living situation [n (%)] | |
With family | 20 (83.3) |
Alone | 4 (16.7) |
Employment [n (%)] | |
Retired | 19 (90.5) |
Working | 2 (9.5) |
Unknown | 3 |
Mean BMI (kg/m 2) | 25.9±4.4 |
Unintentional weight loss in preceding 6 months [n (%)] | |
<5 lbs. | 14 (58.3) |
5–10 lbs. | 6 (25) |
>10 lbs. | 4 (16.7) |
ECOG PS [n (%)] | |
0 | 4 (16.7) |
1 | 9 (37.5) |
2 | 10 (41.7) |
3+ | 1 (4.2) |
Score on the CCI | |
Median | 1 |
Range | 0–4 |
CCI score groups [n (%)] | |
0 | 7 (29.2) |
1 | 8 (33.3) |
2+ | 9 (37.5) |
Of the cancer and prior treatments | |
Tumour type [n (%)] | |
Colorectal cancer | 6 (25) |
Non-small-cell lung cancer | 16 (66.7) |
Small-cell lung cancer | 1 (4.2) |
Mesothelioma | 1 (4.2) |
Stage [n (%)] | |
II | 6 (25) |
III | 3 (12.5) |
IV | 15 (62.5) |
Time since cancer diagnosis (months) | |
Median | 3.5 |
Range | 0–65 |
Prior therapies [n (%)] | |
Chemotherapy | 7 (29.2) |
Radiation | 8 (33.3) |
Resection of primary tumour | 14 (58.3) |
Lines of prior systemic therapy (n) | |
Median | 0 |
Range | 0–5 |
Prior systemic therapy groups [n (%)] | |
0 Lines | 18 (75) |
1 Lines | 3 (12.5) |
2+ Lines | 3 (12.5) |
Of current chemotherapy | |
Agents received [n (%)] | |
1 | 4 (16.7) |
2+ | 20 (83.3) |
Initial dose [n (%)] | |
Standard | 15 (62.5) |
Dose-reduced | 9 (37.5) |
BMI = body mass index; ECOG PS = Eastern Cooperative Oncology Group performance status; CCI = Charlson comorbidity index.