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. 2015 Sep 23;19(12):2832–2841. doi: 10.1111/jcmm.12675

Figure 3.

Figure 3

Ectopic expression of Dickkopf‐related protein 3 (DKK3) disrupted β‐catenin/TCF‐4 signalling and suppresses epithelial–mesenchymal transition in pancreatic cancer Bxpc‐3 cell in hypoxic conditions. (A) Western blotting analysis of cytoplasm and nuclear levels of β‐catenin in hypoxic conditions and hypoxia mimetic conditions. (B) Western blotting analysis of β‐catenin downstream targets gene and stem cell marker Oct‐4 in hypoxic conditions and hypoxia mimetic conditions. (C) Western blotting analysis of epithelial‐mesenchymal transition (EMT) markers in hypoxic conditions and hypoxia mimetic conditions.