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. 2015 Dec 16;10:7467–7475. doi: 10.2147/IJN.S97622

Table 3.

AuNPs induced changes in the level of hepatic GSH, MDA, and NO of mice infected with Schistosoma mansoni

Group GSH (mg/kg) MDA (nmol/g) NO (μmol/g)
Noninfected 47.5±0.4 6±0.2 88±4
Infected 32.6±1.2a 44±2a 129±4a
Infected (+0.25 mg/kg AuNPs) 37.2±2a,b 26±1.5a,b 102±3.7a,b
Infected (+0.5 mg/kg AuNPs) 36.2±1.6a,b 17.5±0.7a,b 97±3.8a,b
Infected (+1 mg/kg AuNPs) 36.2±1.3a,b 35.2±0.2a,b 95±2a,b
Infected (+ PZQ) 35.5±1.2a,b 27.3±1.3a,b 106±2a,b

Notes: Values are mean ± SEM.

a

Significant against noninfected (AuNPs) group at P≤0.05.

b

Significant against infected (AuNPs) group at P≤0.05.

Abbreviations: AuNPs, gold nanoparticles; GSH, reduced glutathione; MDA, malondialdehyde; NO, nitric oxide; PZQ, praziquantel; SEM, standard error of the mean.