. Author manuscript; available in PMC: 2016 May 27.

Published in final edited form as: J Am Chem Soc. 2015 May 14;137(20):6484–6487. doi: 10.1021/jacs.5b03382

Table 1.

Relative HDX Half-Life Change of Octamer 5.

graphic file with name nihms-744133-t0007.jpg

	Phe-1	γ(I)-2	Phe-3	γ(I)-4	Phe-5	γ(I)-6	Phe-7	γ(I)-8
t_½ (hr)	2.2	102	95	199	121	– ^a	46	37
Normalized t_½	1.7	13	73	25	93	– ^a	35	4.6
H-bonded ring size	–	10	12	10	12	10	12	–

Resonance overlapped with phenyl H.