Table 3.

Effect of cholesterol-enriched diet and sitagliptin 125 mg/kg/day on serum inflammatory marker (TNF-α level in pg/mL and hsCRP in mg/L). The data were expressed as mean ± SEM.

Group			TNF-α (pg/mL)	hsCRP (mg/L)
I	Normal group	Zero time	0.60 ± 0.09	3.0 ± 0.0
		6 weeks	1.08 ± 0.11	3.0 ± 0.0
		12 weeks	1.05 ± 0.06	3.0 ± 0.0
II	Induced untreated group	Zero time	0.77 ± 0.10	3.0 ± 0.0
		6 weeks	4.70 ± 0.54*	43 ± 1.8*
		12 weeks	7.05 ± 0.44†	57 ± 3.0†
III	Sitagliptin-treated group	Zero time	0.90 ± 0.10	3.0 ± 0.0
		6 weeks	5.52 ± 0.15*	42 ± 1.6*
		12 weeks	2.50 ± 0.20†	18 ± 1.6†

SEM: standard error of the mean; TNF-α: tumor necrosis factor-α; hsCRP: high-sensitivity C-reactive protein.

^*p < 0.05 (means at 6 weeks versus means at zero time); ^†p < 0.05 (means at 12 weeks versus means at 6 weeks.