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. 2015 Dec 22;10(12):e0145497. doi: 10.1371/journal.pone.0145497

Table 1. List of parameters used for the characterization of MS lesions.

PARAMETER TYPE PARAMETER DESCRIPTION
Diffusion  
1 ADC Apparent Diffusion Coefficient
Texture  
2* Energy Measure of local uniformity of gray levels
3* Entropy Measure of randomness of gray levels
4* Contrast Measure of the amount of gray levels variations
5* Homogeneity Measure of local homogeneity. It increases with less contrast
6* Correlation Measure of linear dependency of gray levels of neighboring pixels
7* Inverse difference moment Measure of local homogeneity of the gray levels
8* Sum average Measure of overall image brightness
9* Sum variance Measure of how spread out the sum of the gray levels of voxel pair is
10* Difference in variance Measure of variation in the difference in gray levels between voxel pairs
11 SRE Short Run Emphasis (first property of run-length distribution)
12 LRE Long Run Emphasis
13 GLN Gray-Level Nonuniformity
14 RLN Run-Length Nonuniformity
15 RP Run percentage
16 LGRE Low Gray-Level Run Emphasis
17 HGRE High Gray-Level Run Emphasis
18 SRLGE Short Run Low Gray-Level Emphasis
19 SRHGE Short Run High Gray-Level Emphasis
20 LRLGE Long Run Low Gray-Level Emphasis
21 LRHGE Long Run High Gray-Level Emphasis

*Parameters derived from the co-occurrence matrix

† Parameters derived from the run length matrix.