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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Prog Neurobiol. 2015 Apr 6;130:29–70. doi: 10.1016/j.pneurobio.2015.03.005

Table 4.

VP manipulations and consummatory effects.

Reference VP Manipulation System Effects Task Result
Inui et al., 2007 Bicuculline GABA GABA-A Antagonist Consumption Increase
Stratford et al., 1999 Bicuculline GABA GABA-A Antagonist Consumption Increase
Stratford and Wirtshafter, 2012 Lesion NA NA Consumption induced by shell muscimol Attenuated
Stratford and Wirtshafter, 2013 Bicuculline GABA GABA-A Antagonist Consumption Increase
Stratford and Wirtshafter, 2013 Bicuculline GABA GABA-A Antagonist Consumption after LH lesion Attenuated
Covelo et al. 2014 Bicuculline GABA GABA-A Antagonist Consumption of fat Increase
Taha et al., 2009 Muscimol GABA GABA-A Agonist Consumption Decrease
Smith et al., 2005 Bicuculline GABA GABA-A Antagonist Consumption Increase
McAlonen et al., 1993 Lesion NA NA Consumption No effect
Smith et al., 2005 DAMGO Opioid Mu agonist Consumption Mixed
Smith et al., 2007 DAMGO Opioid Mu agonist Consumption Increase
Harvey et al., 2002 3-PBC GABA A1 Mixed Saccharin Consumption Decrease
Shimura et al., 2006 Muscimol GABA A Agonist Consumption of Preferred saccharin Decrease
Shimura et al., 2006 Bicuculline GABA GABA-A Antagonist Consumption of Preferred saccharin Increase
Shimura et al., 2006 CNQX Glutamate AMPA Antagonist Consumption of Preferred saccharin Decrease
Shimura et al., 2006 DAMGO Opioid Mu agonist Consumption of Preferred saccharin Mixed
Shimura et al., 2006 SCH-23390 Dopamine D2 Antagonist Consumption of Preferred saccharin Decrease
Shimura et al., 2006 Sulpiride Dopamine D2 agonist Consumption of Preferred saccharin No effect
Shimura et al., 2006 Muscimol GABA GABA-A Agonist Consumption of Nonpreferred quinine Decrease
Shimura et al., 2006 Bicuculline GABA GABA-A Antagonist Consumption of Nonpreferred quinine Decrease
Shimura et al., 2006 CNQX Glutamate AMPA Antagonist Consumption of Nonpreferred quinine No effect
Shimura et al., 2006 DAMGO Opioid Mu agonist Consumption of Nonpreferred quinine Decrease
Shimura et al., 2006 SCH-23390 Dopamine D2 Antagonist Consumption of Nonpreferred quinine No effect
Shimura et al., 2006 Sulpiride Dopamine D2 agonist Consumption of Nonpreferred quinine No effect
Shimura et al., 2006 Muscimol GABA GABA-A Agonist Consumption of Water Decrease
Shimura et al., 2006 Bicuculline GABA GABA-A Antagonist Consumption of Water No effect
Shimura et al., 2006 CNQX Glutamate AMPA Antagonist Consumption of Water No effect
Shimura et al., 2006 DAMGO Opioid Mu agonist Consumption of Water Decrease
Shimura et al., 2006 SCH-23390 Dopamine D2 Antagonist Consumption of Water No effect
Shimura et al., 2006 Sulpiride Dopamine D2 agonist Consumption of Water No effect
Farrar et al., 2008 Muscimol GABA GABA-A Agonist Consumption during food self-administration Mixed
Farrar et al., 2008 Muscimol GABA GABA-A Agonist Consumption of preferred substance Mixed
Taha et al., 2009 Muscimol GABA GABA-A Agonist Consumption induced by Acb DAMGO Blocked
Taha et al., 2009 Lesion NA NA Consumption induced by Acb DAMGO No effect
Smith et al., 2007 VP Naloxone & Acb DAMGO Opioid Antagonist Consumption induced by Acb DAMGO No effect
Smith et al., 2007 VP DAMGO & Acb naloxone Opioid Mu agonist Consumption induced by VP DAMGO Decrease
Johnson et al., 1996b Lesion NA NA Responses during food self-administration Decrease
Fletcher et al., 1998 Amphetamine Dopamine Multiple Responses during food self-administration with conditioned reinforcer Increase
Fletcher et al., 1998 Picrotoxin GABA GABA-A Antagonist Food self-administration with conditioned reinforcer Decrease
Smith et al., 2005 Bicuculline GABA GABA-A Antagonist Food carrying Increase
Smith et al., 2005 DAMGO Opioid Mu agonist Food carrying No effect
Inui et al., 2007 Bicuculline GABA GABA-A Antagonist Hedonic taste reactivity Increase
Smith et al., 2005 Bicuculline GABA GABA-A Antagonist Hedonic taste reactivity No effect
Smith et al., 2005 DAMGO Opioid Mu agonist Hedonic taste reactivity Mixed
Smith et al., 2007 DAMGO Opioid Mu agonist Hedonic taste reactivity Increase
Shimura et al., 2006 Muscimol GABA GABA-A Agonist Hedonic taste reactivity Decrease
Shimura et al., 2006 Bicuculline GABA GABA-A Antagonist Hedonic taste reactivity No effect
Shimura et al., 2006 CNQX Glutamate AMPA Antagonist Hedonic taste reactivity No effect
Shimura et al., 2006 DAMGO Opioid Mu agonist Hedonic taste reactivity No effect
Shimura et al., 2006 SCH-23390 Dopamine D2 Antagonist Hedonic taste reactivity No effect
Inui et al., 2007 Bicuculline GABA GABA-A Antagonist Aversive taste reactivity Decrease
Shimura et al., 2006 Muscimol GABA GABA-A Antagonist Aversive taste reactivity Increase
Shimura et al., 2006 Bicuculline GABA GABA-A Antagonist Aversive taste reactivity No effect
Shimura et al., 2006 CNQX Glutamate AMPA Antagonist Aversive taste reactivity No effect
Shimura et al., 2006 DAMGO Opioid Mu agonist Aversive taste reactivity No effect
Shimura et al., 2006 SCH-23390 Dopamine D2 Antagonist Aversive taste reactivity No effect
Smith et al., 2007 VP Naloxone & Acb DAMGO Opioid Antagonist Taste reactivity induced by Acb DAMGO Blocked
Smith et al., 2007 VP DAMGO & Acb naloxone Opioid Antagonist Taste reactivity induced by VP DAMGO Blocked
Inui et al., 2007 Bicuculline GABA GABA-A Antagonist Taste aversion Blocked

Manipulation refers to an intra-VP injections or VP lesion, unless stated otherwise.