Table 2.

Hydrodynamic size and zeta potential of non-doped and doped fumed silica.

	Primary Size (nm)	Hydrodynamic Size (nm)			Zeta Potential (mV)
		Water	PBS&0.6 mg/mL BSA&0.01 mg/mL DPPC	RPMI 1640&10% Serum	Water	PBS&0.6 mg/mL BSA&0.01 mg/mL DPPC	RPMI 1640&10% Serum
Fumed Silica	16±2	258.2±31.3	211.4±8.6	175.3±12.3	−38.0±5.9	−9.5±4.5	−6.8±2.7
FS-1% Ti	16±2	265.2±11.2	266.5±7.8#	136.0±17.3$	−30.9±2.1	−9.1±7.9	−9.1±2.6
FS-3% Ti	16±2	182.2±4.2*	183.3±15.9	189.8±10.1	−32.0±3.2	−8.7±5.3	−13.9±8.8
FS-5% Ti	16±1	300.0±43.5	334.3±29.9#	163.2±6.2	−34.7±7.1	−11.6±3.3	−8.6±4.6
FS-7% Ti	16±1	247.4±16.7	140.1±29.8#	65.2±16.4$	−34.2±1.1	−15.7±2.4	−10.4±6.6
FS-1% Al	16±1	273.2±15.1	229.4±8.3	117.3±3.7$	−32.3±4.9	−11.6±7.0	−10.0±3.2
FS-3% Al	16±1	255.7±7.0	293.5±54.6	191.4±6.9	−35.6±2.8	−9.5±5.0	−11.7±5.8
FS-5% Al	16±2	328.3±26.0*	252.4±11.6#	189.6±10.1	−27.1±4.7	−11.7±6.5	−6.2±4.6
FS-7% Al	16±1	161.0±1.3*	149.5±7.6#	157.8±1.0	−36.9±2.7	−13.2±20.3	−10.7±2.1

^*p<0.05 compared to size of non-doped fumed silica in water;

^#p<0.05 compared to size of non-doped fumed silica in PBS&0.6 mg/mL BSA&0.01 mg/mL DPPC;

^$p<0.05 compared to size of non-doped fumed silica in RPMI 1640 &10% Serum.