Figure 1.
Flow diagram showing disorders of immune deficiency or dysregulation with variable levels of peripheral and tissue eosinophilia. Characteristics of each disorder are listed once under the most prevalently featured category. AD-HIES: autosomal dominant hyper IgE syndrome, DOCK8: Dedicator of cytokinesis 8, PGM3: Phosphoglucomutase 3, ADA-SCID: Adenosine deaminase-severe combined immunodeficiency, ALPS: autoimmune lymphoproliferative syndrome, IPEX: Immunodysregulation, polyendocrinopathy, enteropathy, X-linked syndrome, LDS: Loeys-Dietz syndrome, SAM: severe dermatitis, multiple allergies, and metabolic wasting, WAS: Wiskott-Aldrich syndrome