Table 4. rs76763715 relates to more rapid progression of Hoehn and Yahr stage.
P values for association of Hoehn and Yahr stage for cases in the combined WU and PPMI dataset are shown. Cases with at least 3 scores measured over a minimum of 1 year were included.
| SNP | Chr | Nearest Gene (s) | p value |
|---|---|---|---|
| rs76763715 | 1 | GBA (N370S) | 9.0E-04 |
| rs75548401 | 1 | GBA (K26R) | 0.682 |
| rs10928513 | 2 | ACMSD/TMEM163 | 0.576 |
| rs6723108 | 2 | ACMSD/TMEM163 | 0.599 |
| rs2390669 | 2 | STK39 | 0.107 |
| rs11711441 | 3 | MCCC1/LAMP3 | 0.495 |
| rs6599388 | 4 | GAK/TMEM175 | 0.206 |
| rs356219 | 4 | SNCA | 0.575 |
| rs11931074 | 4 | SNCA | 0.812 |
| rs356220 | 4 | SNCA | 0.622 |
| rs356165 | 4 | SNCA | 0.591 |
| rs3822086 | 4 | SNCA | 0.820 |
| rs3857059 | 4 | SNCA | 0.821 |
| rs2736990 | 4 | SNCA | 0.287 |
| rs2942168 | 17 | CRHR1/MAPT | 0.456 |
| rs393152 | 17 | CRHR1/MAPT | 0.380 |
| rs7215239 | 17 | CRHR1/MAPT | 0.461 |
| rs1981997 | 17 | MAPT | 0.456 |
| rs1052553 | 17 | MAPT | 0.456 |
| rs17652121 | 17 | MAPT | 0.456 |
| rs8070723 | 17 | MAPT | 0.465 |
| rs199533 | 17 | NSF/MAPT | 0.744 |