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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Dev Biol. 2015 Oct 13;408(1):56–65. doi: 10.1016/j.ydbio.2015.10.002

Figure 6. Deletion of ERK phosphorylation reduces cell migration.

Figure 6

Panel A: Endodermal explants from both control and MEKDN/+; Gata5-Cre lungs were treated with FGF10-soaked beads. The control explants move towards FGF10 source after 8 hr culture. In opposite, MEKDN/+; Gata5-Cre explants show no sign of movement. Panel B: Epithelial cells from E12.5 lungs were cultured and wounded. After 12 hour, the control cells show 66% wound healing, where as MEK inhibitor treated cells show 20% (Panel C).