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Antonie Van Leeuwenhoek’s illustrations of various bacteria isolated from a human mouth that was published in September 1683, which he referred to as “animalcules.” Bacteria shown are (A) a rod-shaped bacterium, (B) a motile bacterium moving from points (C) to (D), (E) micrococci, (F) fusiform bacteria and (G) a spirochete illustrating characteristic wave-like shape. Adapted from [5].
