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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Curr Opin Cell Biol. 2015 Nov 11;37:49–60. doi: 10.1016/j.ceb.2015.09.002

Figure 2. Mechanisms of ICL repair.

Figure 2

Two mechanisms of ICL repair are depicted. (A) The fork convergence pathway, in which ICL repair is triggered when two forks converge on the lesion. (B) The fork traverse pathway, in which a single fork bypasses an ICL without unhooking the parental strands. Incisions are represented by orange arrows.