Table 1.
Characteristics | Direct (N = 152) | Transfer (N = 210) | P value |
---|---|---|---|
Demographics | |||
Age (mean ± SD) | 59.8 ± 13.8 | 64 ± 15.2 | <.01 |
Males (%) | 58.5 | 55.2 | .53 |
Hypertension (%) | 80.2 | 80.9 | .87 |
Diabetes (%) | 23.0 | 31.4 | .08 |
Coagulation disorder (%) | 2.6 | 4.7 | .30 |
Atrial fibrillation (%) | 4.6 | 10.9 | .03 |
Coronary disease/MI (%) | 9.2 | 15.7 | .07 |
Past history of ICH (%) | 9.9 | 9.1 | .79 |
History of substance abuse (%) | 17.1 | 10.0 | .05 |
Onset to CSC arrival time (h, median/IQR) | 1.7/.8–4.3 | 6.2/4.3–11.7 | <.01 |
Onset-to-arrival categories (%) | |||
< 12 h | 61.8 | 37.1 | <.01 |
12–24 h | 4.6 | 10.5 | .04 |
> 24 h or unknown | 33.6 | 52.4 | <.01 |
Mode of transportation (%) | |||
Ambulance | 67.6 | 67 | .37 |
Air | 26.5 | 32.5 | |
GCS score at CSC arrival (median/IQR) | 10/4.5–14 | 13/7–15 | .02 |
NIHSS score at CSC arrival (median/IQR) | 18/12–32 | 12/3–25 | <.01 |
Platelets (median/IQR) | 207/161.5–252 | 204.5/168–254 | .31 |
INR (median/IQR) | 1.01/.9–1.1 | 1.05/1.0–1.1 | .13 |
PTT (median/IQR) | 28.9/26–32 | 29.6/27.2–33.2 | .40 |
ICH characteristics | |||
ICH score (median/IQR) | 2/1–3 | 1/1–3 | <.01 |
ICH volume (median/IQR) | 20.5/8.7–47.9 | 15.2/3.6–39.1 | <.01 |
ICH location (%) | |||
Basal ganglia | 28.9 | 20.5 | .06 |
Thalamus | 34.8 | 25.7 | .06 |
Lobar | 26.3 | 39.1 | .01 |
Brain stem | 5.9 | 4.3 | .48 |
Cerebellar | 3.3 | 7.1 | .12 |
Pure IVH | .6 | 3.3 | .12 |
IVH present (%) | 60.5 | 45.2 | <.01 |
Supratentorial ICH < 5 cc (%) | 8.6 | 20.5 | <.01 |
Neuroworsening | 32.9 | 22.4 | .03 |
Abbreviations: CSC, comprehensive stroke center; GCS, Glasgow Coma Scale; ICH, intracerebral hemorrhage; INR, international normalized ratio; IQR, interquartile range; IVH, intraventricular hemorrhage; MI, myocardial infarction; NIHSS, National Institutes of Health Stroke Scale; PTT, partial thromboplastin time; SD, standard deviation.
Arrival time refers to the time each patient arrived at the CSC.