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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Neurogastroenterol Motil. 2015 Oct 14;28(1):43–53. doi: 10.1111/nmo.12695

Figure 1.

Figure 1

(A) Experimental paradigm. Adolescent IBS patients and age-matched healthy controls underwent two runs of fMRI during each of the subliminal and liminal rectal distension conditions. (B) Sample hemodynamical response to subliminal rectal distension at one activated voxel in the ACC area of an IBS patient. The red line denotes the ideal response to the rectal distension sequence, the black line is the actual BOLD response, and the blue line is the fitted response generated by the regression analysis.