Table 1. Anthropometric characteristics of the study population stratified by ethnicity and TM6SF2 Genotype.

	Total Population	Caucasians			African Americans			Hispanics
	N=957	CC (n=353)	CT (n=49)	P	CC (n= 249)	CT/TT (n=17)	P	CC (n=263)	CT/TT (n=26)	P
Age (years)	13.338 ± 3.43	13.796 ± 3.65	13.657 ± 2.68	0.797	13.353 ± 3.43	13.235 ± 3.57	0.891	12.776 ± 3.701	13.342 ± 2.857	0.447
Gender (M/F) %	40/60	39/61	37/63	0.445	39/61	41/59	0.51	42/58	50/50	0.287
Glucose tolerance (NGT/IGT/T2D) %	73/22/5	74/22/4	67/27/6	0.548	70/22/8	88/12/0	0.39	76/20/4	61/31/8	0.285
BMI (kg/m2)	32.959 ± 7.601	32.744 ± 7.40	32.35 ± 8.03	0.733	34.417 ± 7.97	34.199 ± 8.44	0.914	31.872 ± 7.12	31.787 ± 6.97	0.954
Z-score BMI	2.158 ± 0.69	2.126 ± 0.66	1.954 ± 0.89	0.117	2.284 ± 0.56	2.203 ± 0.88	0.595	2.124 ± 0.77	2.058 ± 0.70	0.683
Body Fat (%)	42.397 ± 10.21	42.365 ± 10.07	39.198 ± 10.03	0.048	44.137 ± 10.43	44.421 ± 9.91	0.921	41.737 ± 9.9	40.044 ± 10.43	0.419
Metabolic Syndrome %	61/39	67/33	70/30	0.412	76/24	60/40	0.153	23/77	33/67	0.196
Body Fat Composition
	N=454	CC (n=155)	CT (n=28)	P	CC (n=116)	CT/TT (n=5)	P	CC (n=134)	CT (n=16)	P
Visceral (cm2)	53.65 ± 28.53	57.414 ± 28.71	53.454 ± 30.75	0.504	43.55 ± 24.16	56.62 ± 24.17	0.552	57.706 ± 29.39	56.963 ± 29.62	0.727
Deep Subcutaneous (cm2)	151.35 ± 75.84	148.01 ± 72.99	131.63 ± 78.01	0.057	155.808 ±83.25	179.98 ± 64.37	0.839	157.37 ±76.32	144.731 ±78.62	0.950
Subcutaneous (cm2)	455.39 ±214.99	456.16±206.32	389.725±198.87	0.003	472.804±231.9	600.48 ± 170.10	0.36	452.789±209.3	434.431±250.1	0.953
Superficial Subcutaneous (cm2)	129.146 ± 65.19	130.369±61.55	109.725 ± 57.11	0.003	141.896±70.84	186.88 ± 58.00	0.325	121.779±63.91	111.475±63.64	0.699
Deep/Superficial Subcutaneous	1.233 ± 0.525	1.187 ± 0.47	1.238 ± 0.51	0.802	1.144 ± 0.55	1.011 ± 0.44	0.51	1.371 ± 0.56	1.348 ± 0.50	0.806
Hepatic Fat Content (%)	7.17 ± 10.43	6.679 ± 9.71	10.911 ± 13.83	0.031	2.9 ± 6.811	9.14 ± 11.62	0.02	9.931 ± 11.27	12.081 ± 12.98	0.602