TABLE 2.
Measures of adiposity and levels of soluble adhesion proteins by sex-adjusted for race/ethnicity measured at Exam 2 unless otherwise specified, mean (standard deviation) or percentage
| Characteristics | Females | Males | P-valuea |
|---|---|---|---|
| Age, years | 64 (10) | 64 (10) | 0.74 |
| Body mass index, kg/m2 | 29 (6) | 28 (4) | <0.001 |
| Waist circumference, cm | 97 (16) | 100 (12) | <0.001 |
| Waist to hip ratio, % | <0.001 | ||
| Men ≤ 0.95, women ≤ 0.80 | 12 | 41 | |
| Men 0.96–1.0, women 0.81–0.85 | 16 | 34 | |
| Men > 1.0, women > 0.85 | 71 | 25 | |
| CT measures of fat, Exam 2/3 | |||
| VAT, cm2 | 0.54 (0.16) | 0.64 (0.14) | <0.001 |
| SAT, cm2 | 0.95 (0.03) | 0.91 (0.04) | <0.001 |
| Soluble Adhesion Proteins | |||
| sP-selectin, ng/mL (n = 5,974) | 35 (12) | 39 (13) | <0.001 |
| sL-selectin, ng/mL (n = 2,372) | 931 (200) | 847 (190) | <0.001 |
| sVCAM-1, ng/mL (n = 2,372) | 730 (225) | 746 (235) | 0.2 |
| sICAM-1, ng/mL (n = 2,343) | 255 (87) | 251 (86) | 0.56 |
| sHGF, ng/mL (n = 2,358) | 1,002 (234) | 965 (226) | 0.001 |
a
Sex comparisons from regression models adjusting for race/ethnicity.
CT, computed tomography; VAT, visceral adipose tissue; SAT, subcutaneous adipose tissue; VCAM-1, vascular cell adhesion molecule-1; ICAM-1, intercellular adhesion molecule; HGF, hepatocyte growth factor.