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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Clin Genet. 2015 Jul 14;89(3):285–294. doi: 10.1111/cge.12630

Fig. 2.

Fig. 2

Venn diagrams of the cancers identified in BAP1 patients and families. (a) Individuals with BAP1 mutations diagnosed with uveal melanoma (UM), renal cell carcinoma (RCC), cutaneous melanoma (CM), and/or malignant mesothelioma (MMe). There are 118 patients who were diagnosed with at least one of the above cancers. Thirty individuals were only diagnosed with another cancer uncertain to be BAP1 related. Twelve individuals were diagnosed with atypical Spitz tumors (ASTs) only. Fourteen individuals were unaffected. (b) Families with BAP1 mutations with mutation-positive members diagnosed with UM, RCC, CM, and MMe. There were 57 families reported, of which 54 had at least member with one of the above diagnoses testing positive. One family presented with only ASTs and another cancer uncertain to be BAP1 related. Two families had a history of one of the above diagnoses, but those members were not tested.