Table 3.
Specific drug of causing DILI
| Category | Specific drug | Cases (n) | Percentage (%) |
|---|---|---|---|
| Chinese herbal medicine | Herbal medicine ingredients | 91 | 70.00 |
| Radix polygoni multiflori | 15 | 11.54 | |
| Panax pseudo-ginseng | 10 | 7.69 | |
| Tripterygium wilfordii | 6 | 4.62 | |
| Saffron | 4 | 3.08 | |
| And shenbao mixture | 4 | 3.08 | |
| Antithyroid | Propylthiouracil | 26 | 50 |
| Methimazole | 26 | 50 | |
| Antituberculosis | Isoniazid + rifampicin + pyrazinamide | 29 | 56.86 |
| Isoniazid + rifampicin | 17 | 33.33 | |
| Rifampicin | 4 | 7.85 | |
| Isoniazid + pyrazinamide | 1 | 1.96 | |
| Antibiotics | Quinolones | 7 | 26.92 |
| Cephalosporin | 6 | 23.08 | |
| United | 4 | 15.38 | |
| Acyclovir | 3 | 11.53 | |
| Vancomycin | 2 | 7.70 | |
| Meropenem | 2 | 7.70 | |
| Biaxin | 2 | 7.70 | |
| Chemotherapy drugs | Docetaxel + platinum | 10 | 45.45 |
| Platinum | 4 | 18.18 | |
| Etoposide | 4 | 18.18 | |
| Gemcitabine | 3 | 13.64 | |
| Imatinib | 1 | 4.55 | |
| Immunosuppressants | Leflunomide | 6 | 27.27 |
| Methotrexate | 5 | 22.73 | |
| Acipimox | 3 | 13.64 | |
| Thalidomide | 3 | 13.64 | |
| Cyclosporin | 3 | 13.64 | |
| Phenylbutazone | 2 | 9.09 | |
| Antipyretics and analgesics | Acetyl aminophenol | 9 | 69.23 |
| Meloxicam | 2 | 15.38 | |
| Celecoxib | 2 | 15.38 | |
| Psychotropic drugs | Clozapine | 3 | 27.27 |
| Olanzapine | 2 | 18.18 | |
| Carbamazepine | 2 | 18.18 | |
| Dilantin sodium | 2 | 18.18 | |
| Lithium carbonate | 2 | 18.18 | |
| Antidiabetics | Metformin | 5 | 55.56 |
| Gliclazide | 2 | 22.22 | |
| Acarbose | 2 | 22.22 | |
| Lipid-lowering drugs | Statins | 8 | 100 |