Figure 4.

Infection induced transcription of anti-apoptotic factors in the presence or absence of host translation. Cell lines were plated in six well plates and infected for 30 h prior to lysis and RNA extraction. Relative expression was normalized to host GAPDH and then the ratio of infected vs. uninfected gene expression was determined in human cells (A–C), mouse cells (D–F) and guinea pig cells (G–I). ^**p < 0.01, ^*p < 0.05 (representative of three independent trials).