Table 1.
Mass spectrometry-based identification of dystrophin and closely associated proteins.
The proteomic profiling of the dystrophin-glycoprotein complex and associated proteins was carried out by LC-MS/MS analysis using the microsomal fraction from mouse skeletal muscle [80].
| Accession No. | Protein name | Coverage (%) | Unique peptides | Molecular mass (kDa) |
|---|---|---|---|---|
| P11531 | Dystrophin Dp427-M | 10.85 | 26 | 425.6 |
| Q62165 | Dystroglycan | 10.41 | 9 | 96.8 |
| P82350 | Sarcoglycan, alpha | 19.12 | 6 | 43.3 |
| P82349 | Sarcoglycan, beta | 29.06 | 5 | 34.9 |
| P82347 | Sarcoglycan, delta | 18.34 | 4 | 32.1 |
| P82348 | Sarcoglycan, gamma | 14.78 | 4 | 32.1 |
| Q62147 | Sarcospan | 4.17 | 1 | 23.8 |
| Q9D2N4 | Dystrobrevin, alpha | 5.63 | 3 | 84.0 |
| Q61234 | Syntrophin, alpha-1 | 7.95 | 3 | 53.6 |
| Q60675 | Laminin, alpha-2 | 7.60 | 13 | 343.6 |
| P02469 | Laminin, beta-1 | 2.13 | 3 | 197.0 |
| Q61292 | Laminin, beta-2 | 2.33 | 3 | 196.5 |
| P02468 | Laminin, gamma-1 | 9.15 | 10 | 177.2 |