Table 1.
3-D blast hits of C-terminal domain of PfPLP1
| PDB ID | Name of protein | TM-score | RMSD | IDEN | Cov. | |
|---|---|---|---|---|---|---|
| 1 | 3nsjA | Lymphocyte perforin | 0.677 | 1.35 | 0.073 | 0.719 |
| 2 | 1rlw | C2 domain of calcium-phospholipid binding domain from cytosolic phospholipase A2 | 0.621 | 2.03 | 0.083 | 0.712 |
| 3 | 3w56A | Structure of a C2 domain | 0.61 | 1.68 | 0.078 | 0.673 |
| 4 | 4npjA | Structure and ca(2+)-binding properties of the tandem c2 domains of e-syt2. Extended-Synaptotagmin 2, C2A- and C2B-domains | 0.608 | 2.31 | 0.064 | 0.712 |
| 5 | 3kwuA | Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis | 0.604 | 2.19 | 0.083 | 0.706 |
| 6 | 1djiB4 | A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1 | 0.604 | 2.3 | 0.1 | 0.712 |
| 7 | 1djxB | C2 domain of Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C | 0.604 | 2.31 | 0.091 | 0.712 |
| 8 | 3kwtA | Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis | 0.598 | 2.17 | 0.085 | 0.693 |
| 9 | 2ep6A | Solution structure of the second C2 domain from human MCTP2 protein | 0.598 | 2.3 | 0.065 | 0.706 |
| 10 | 4ihbA | X-RAY Structure of the canonical C2A domain from human dysferlin | 0.596 | 2.4 | 0.074 | 0.706 |
| 11 | 2b3rB | Crystal structure of the C2 domain of class II phosphatidylinositide 3-kinase C2 | 0.541 | 2.68 | 0.078 | 0.66 |
| 12 | 1djgA | A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1 | 0.602 | 2.47 | 0.1 | 0.719 |
| 13 | 1w15A | Rat synaptotagmin 4 C2B domain in the presence of calcium | 0.518 | 2.43 | 0.073 | 0.614 |
| 14 | 2uzpA | Crystal structure of the C2 domain of human protein kinase C gamma | 0.528 | 2.75 | 0.083 | 0.647 |
TM-score: TM-score is an algorithm to calculate the structural similarity of two protein models. TM-score has the value in (0,1]. Based on statistics, a TM-score <0.17 corresponds to a random similarity and a TM-score >0.5 generally corresponds to the same fold; RMSD: The root-mean-square deviation (RMSD) is the measure of the average distance between the atoms (usually the backbone atoms) of superimposed proteins; IDEN: IDEN is the percentage sequence identity in the structurally aligned region; Cov.: Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein