Table 1.

Colonic mucosa pathology and PCNA (^-x ± s, %)

Pathological diagnosis	PCNA-area rate	PCNA-labeling index
Normal colonic mucosa	12.8 ± 2.5	32.8 ± 5.8
Hyperplastic polyp	18.2 ± 5.7	27.6 ± 10.3
Tubular adenoma with low-grade atypia	31.0 ± 8.1	40.9 ± 11.8
Tubular adenoma with high-grade atypia	44.6 ± 10.1	59.2 ± 9.8
Adenocarcinoma	69.2 ± 11.8	74.3 ± 13.6
Serrated adenoma (upper zone)	16.4 ± 7.5	25.6 ± 6.1
Serrated adenoma (middle zone)	31.9 ± 9.9	40.4 ± 8.9
Serrated adenoma (lower zone)	49.6 ± 11.6	60.2 ± 10.1