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Bone marrow nucleated cells in mice bearing CT-26 treated by BAM, 5-FU and MMC
| Exp. | Drug | Dose** (mg/kg) | No. of mice |
Nucleated cells (106/femur) |
|
| x- ± s | % | ||||
| I | Control | 6 | 13 ± 3 | 100 | |
| BAM | 10 | 6 | 13 ± 3 | 100 | |
| MMC | 1 | 5 | 7 ± 2 | 54b | |
| 5-FU | 27 | 6 | 7 ± 2 | 54b | |
| II | Control | 9 | 12 ± 3 | 100 | |
| BAM | 10 | 9 | 12 ± 2 | 100 | |
| MMC | 1 | 8 | 3 ± 1 | 25b | |
| 5-FU | 27 | 8 | 4 ± 1 | 33b | |
*Drugs were administered at equitoxic doses (1/9 LD50).
P < 0.01, vs control group.
