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. 2001 Jun 15;7(3):352–356. doi: 10.3748/wjg.v7.i3.352

Table 2.

APC gene mutation

DNA Region Codon Mutation Amino acid exchange
N 3 CRC A 1354 TTT→TTA Phe→Leu
N17 CRC A 1309 GAA→TAA Stop cocon
N14 CRC B 1389 TCT→TTT Ser→Phe
N 5 CRC B 1357 GGA→AGA Gly→Arg
N21 CRC B 1365 GGT→GGC nonsense
N26 CRC B 1398 AGT→ACT Ser→Thr
N28 CRC C 1465 GTG→GCG Val→Ala
N33 CRC D 1547 GAA→TAA Stop codon
Tubular villous adenoma A 1301 ins1 A Stop codon
Villous adenoma A 1309 GAA→TAA Stop codon
Villous adenoma C 1490 ins8 TTATTACA Frame shift
Tubular villous adenoma B 1367 CAG→CAC Gln→His
ACF A 1309 GAA→TAA Stop codon