Scanning electronmicroscopic observation of changes in human hepatoma cell membranes treated with 0, 0.5, 1, 2 μmol/L As2O3 for 96 h. There were abundant processes and micro villi on the surface of BEL-7402 cells in 0 μmol/L As2O3 group (A). The processes and micro villi was much less in 0.5 μmol/L As2O3 group (B). The processes and micro villi were lost when treated with 1, 2 μmol/L As2O3 (C, D).