Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Dose–response relationship of TPIMS inhibitors and hAS3MT activity. The activity of hAS3MT was assayed as described in the legend to Figure 1 in the presence of the indicated concentrations of (A) TPI-2; (B) TPI-4; (C) TPI-5; or (D) TPI-6. The inhibitor concentrations of half-maximal inhibition (IC50) were calculated as 38 μM for TPI-2, 51 μM for TPI-5, 31 μM for TPI-5, and 38 μM for TPI-6. The data were fitted using SigmaPlot. The data are the mean ± SE (n = 3).
