Figure 13.
MPPs are retained in the cervicovaginal tract. (A) Overlay of particle fluorescence intensity and photographic images for conventional nanoparticles (CPs) and mucus-penetrating particles (MPPs) in the entire cervicovaginal tract tissue. (B) Percent of particles remaining over time on the basis of quantification of particle fluorescence in (A). Adapted from Ensign et al.219 Reprinted with permission from reference 219. Copyright 2012 American Association for the Advancement of Science.