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. 2015 Dec 22;15:1277. doi: 10.1186/s12889-015-2653-x

Table 3.

Univariate and multivariate Cox proportional hazard models: the association of treatment careers and co-factors with mortality in the DC WIHS (n = 329)

Variables Univariate analysis P value Multivariate analysis P value
HR (95 % CI) HR (95 % CI)
Race 0 · 09 0 · 94
 White Referent
 Black 2 · 49 (1 · 08,5 · 76) 0 · 03 1 · 2 (0 · 47,3 · 07) 0 · 71
 Hispanic 1 · 02 (0 · 26,4 · 09) 0 · 98 0 · 81 (0 · 15,4 · 31) 0 · 8
 Other 1 · 88 (0 · 38,9 · 35) 0 · 44 1 · 25 (0 · 14,11 · 13) 0 · 84
Education
  < 12 years Referent
  > = 12 years 0 · 75 (0 · 46,1 · 24) 0 · 26
Age 1 · 05 (1 · 03,1 · 08) 0 · 0003 1 · 06 (1 · 02,1 · 09) 0 · 004
Housinga
 No housing Referent
 Housing 0 · 86 (0 · 48,1 · 53) 0 · 6
Depressiona
 Depression score <16 Referent
Depression score > =16 1 · 71 (1 · 02,2 · 86) 0 · 04 0 · 94 (0 · 54,1 · 64) 0 · 83
Drug Abusea
 No reported drug use Referent
 Reported drug use 2 · 01 (1 · 2,3 · 37) 0 · 008 1 · 57 (0 · 91,2 · 7) 0 · 11
CD4a 0 · 65 (0 · 56,0 · 75) <0 · 0001 0 · 69 (0 · 6,0 · 8) <·0001
ARTa
 No ART use Referent
 ART use 1 · 69 (0 · 97,2 · 93) 0 · 06 1 · 09 (0 · 58,2 · 04) 0 · 8
cARTa
 No cART use Referent
 cART use 1 · 06 (0 · 62,1 · 8) 0 · 84
Adherencea
 < 95 % therapy use Referent
 > = 95 % therapy use 0 · 64 (0 · 32,1 · 27) 0 · 2
HIV treatment career <0 · 0001 <·0001
 Nonviremia Referent
 Intermittent 0 · 83 (0 · 31,2 · 24) 0 · 71 0 · 59 (0 · 18,1 · 94) 0 · 38
 Viremia 5 · 25 (2 · 4,11 · 47) <0 · 0001 3 · 967 (1 · 53,10 · 28) 0 · 0045
Alcohol use > = 7 drinks/week since last visita 1 · 432 (0 · 704,2 · 912) 0 · 322

Multivariate model included race, age, depression, drug abuse, CD4, ART and HIV treatment career

Abbreviations: CI 95 % confident interval, CES-D Center for Epidemiologic studies of depression scale, cART highly active antiretroviral therapy, HR Hazard ratio

a: time-dependent variables