Table 1.
Results of the modular enrichment analysis in the GeneCodis3 database
| Genes | NGR | TNGR | NG | TNG | Hyp | Hyp* | Annotations |
|---|---|---|---|---|---|---|---|
| 6 | 107 | 34,208 | 6 | 7 | 5.67 × 10−15 | 2.84 × 10−14 | Panther pathways P00006: Apoptosis signalling pathway |
| 3 | 5 | 34,208 | 3 | 7 | 5.25 × 10−11 | 8.74 × 10−11 | KEGG 04141: Protein processing in endoplasmic reticulum KEGG 04722: Neurotrophin signalling pathway KEGG 05200: Pathways in cancer KEGG 05152: Tuberculosis Panther pathways P00006: Apoptosis signalling pathway KEGG 05210: Colorectal cancer |
| 4 | 37 | 34,208 | 4 | 7 | 4.04 × 10−11 | 1.01 × 10−10 | KEGG 05200: Pathways in cancer Panther pathways P00006: Apoptosis signalling pathway |
| 3 | 9 | 34,208 | 3 | 7 | 4.40 × 10−10 | 5.51 × 10−10 | KEGG 05200: Pathways in cancer KEGG 05014: Amyotrophic Lateral Sclerosis (ALS) Panther pathways P00006: Apoptosis signalling pathway KEGG 04210: Apoptosis |
| 3 | 26 | 34,208 | 3 | 7 | 1.36 × 10−08 | 1.36 × 10−08 | KEGG 05200: Pathways in cancer KEGG 05145: Toxoplasmosis Panther pathways P00006: Apoptosis signalling pathway |
p values have been obtained through Hypergeometric analysis corrected by the False Discovery Ratio (FDR) method. Annotations selected were KEGG and PANTHER pathways
NGR number of annotated genes in the reference list, TNGR total number of genes in the reference list, NG number of annotated genes in the input list, TNG total number of genes in the input list, Hyp Hypergeometric p value, Hyp* corrected hypergeometric p value