Spatiotemporal characteristics of fast IOSs. A 10-ms flash stimulus was used for retinal stimulation of the frog eye. Raw OCT images were collected with a frame rate of 500 Hz. Stimulus onset is indicated by time “0.” (a) The OCT B-scan image consisted of , corresponding to . Illustrated OCT B-scan images are displayed with a linear scale. The IOS distribution map is superimposed on the OCT B-scan image. (b) Temporal curves of the averaged positive and negative IOSs. (c) To better visualize the IOS onset times, an enlarged profile of the early 14 ms period is illustrated. (d1–d6) Positive IOSs of individual pixels; both raw data (labeled with a star in red) and fitted curves (in blue) are shown. (d1) (, ) and (d2) (, ) were selected from the same axial location at adjacent locations in a lateral direction. (d3) (, ) and (d4) (, ) also share the same axial location but with different lateral positions. (d5) (, ) and (d6) (, ) are the same locations. (e1–e3) Negative IOSs of individual pixels; both raw data (labeled with a star in green) and fitted curve (in blue) are shown. (e1) (, ), (e2) (, ), and (e3) (, ) are from different locations. Scale bars indicate . Reprinted with permission from Ref. 130.