Table 1.
Patient characteristics by age group
| Variables | Age group
|
P-value | |
|---|---|---|---|
| <50 years (n=135) | ≥50 years (n=155) | ||
| Sex (male/female) | 125/10 | 134/21 | 0.091 |
| Blood type (A/B/AB/O) | 49/15/32/39 | 52/17/49/37 | 0.481 |
| Liver cirrhosis (%) | 117 (86.7) | 145 (93.5) | 0.048 |
| HBV (%) | 123 (91.1) | 146 (94.2) | 0.312 |
| HCV (%) | 1 (0.7) | 1 (0.6) | 1.000 |
| AFP level (<400 ng/mL, ≥400 ng/mL) | 81/54 | 114/41 | 0.014 |
| Multinodular (%) | 55 (40.7) | 72 (46.5) | 0.328 |
| Tumor size (≤5 cm, >5 cm) | 70/65 | 99/56 | 0.038 |
| Histologic grade (differentiated/undifferentiated) | 104/31 | 135/20 | 0.025 |
| Child–Pugh status (A/B/C) | 74/47/14 | 74/62/19 | 0.484 |
| Microvascular invasion (%) | 37 (27.4) | 29 (18.7) | 0.078 |
| Portal lymph node metastasis (%) | 27 (20) | 11 (7.1) | 0.001 |
| Milan criteria (in/out) | 48/87 | 54/101 | 0.903 |
| HCC recurrence (%) | 65 (48.1) | 56 (36.1) | 0.038 |
| Number of deaths (%) | 75 (55.6) | 68 (43.9) | – |
Abbreviations: AFP, alpha-fetoprotein; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; HCV, hepatitis C virus.